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DTSTART;TZID=America/Los_Angeles:20251204T114000
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DTSTAMP:20260519T151211
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SUMMARY:BME 280B Seminar: Gali Bai & David Haussler
DESCRIPTION:Presenter 1: Gali Bai\, BME/PBSE Doctoral Candidate\, Brooks Lab\, UC Santa Cruz \nTitle 1: Dissecting the contribution of chromatin accessibility to RNA transcription and processing with long-read sequencing \nDescription: Although all cells in an organism share the same genomic sequence\, transcriptional programs vary dramatically across cell types. This diversity is governed by epigenetic regulation involving the coordinated activities of chromatin remodelers\, histone modifiers\, and histone chaperones that precisely modulate chromatin accessibility. While previous studies have shown that chromatin accessibility at DNase I–hypersensitive sites such as promoters and enhancers is closely associated with gene expression\, much less is known about how chromatin influences transcription and RNA processing. To study how chromatin regulates RNA processing\, we perturbed yeast chromatin accessibility by deleting two highly conserved chromatin remodelers ISW1 and CHD1. With Oxford Nanopore long-read sequencing\, we profiled nascent RNA\, full-length mRNA\, and chromatin fibers in wild-type and chd1 isw1 double-mutant yeast cells. Loss of ISW1 and CHD1 led to increased chromatin accessibility within intragenic regions\, accompanied by aberrant transcription initiation. Leveraging long-read data\, we associated distinct chromatin states with specific RNA processing events and isoform expression outcomes. Despite a similar level of chromatin perturbations across the genome\, genes with low baseline expression showed extensive transcriptional reprogramming\, whereas highly expressed genes remained largely unaffected. These discrepancies can be partially explained by differences in the enrichment of transcription initiation motifs. In intron-containing genes\, loss of ISW1 and CHD1 reduced splicing efficiency and increased intron retention\, likely due to disrupted RNAPII elongation in the double mutant. Together\, our findings highlight the crucial role of ATP-dependent chromatin remodelers in maintaining nucleosome organization and coordinating co-transcriptional RNA processing. \nPresenter 2: David Haussler\, Distinguished Professor\, UC Santa Cruz \nTitle 2: Brain Organoids \nBio: Haussler received his PhD in computer science from the University of Colorado at Boulder. He is a member of the National Academy of Sciences\, the National Academy of Engineering\, the American Academy of Arts and Sciences and a fellow of AAAS and AAAI. He has won a number of awards\, including the 2015 Dan David Prize\, the 2011 Weldon Memorial Prize from University of Oxford\, the 2009 ASHG Curt Stern Award in Human Genetics\, the 2008 Senior Scientist Accomplishment Award from the International Society for Computational Biology\, the 2005 Dickson Prize for Science from Carnegie Mellon University\, and the 2003 ACM/AAAI Allen Newell Award in Artificial Intelligence. \nHosted by: Professor Josh Stuart\, BME Department
URL:https://events.ucsc.edu/event/bme-280b-seminar-gali-bai-david-haussler/
LOCATION:Physical Sciences Building\, Physical Sciences Building\, Santa Cruz\, CA\, 95064
CATEGORIES:Lectures & Presentations,Seminars
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DTSTART;TZID=America/Los_Angeles:20251204T120000
DTEND;TZID=America/Los_Angeles:20251204T133000
DTSTAMP:20260519T151211
CREATED:20251124T181437Z
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SUMMARY:Pemulai ke Nanga Jela/Return to Nanga Jela
DESCRIPTION:About the Talk: The history of hinterland communities is largely written in remote landscapes that today are often targeted for infrastructural development that forcibly relocates existing residents and transforms the land\, obliterating those histories\, and weakening communities. \nIn 1984/5 the Iban longhouse at Nanga Jela on Sarawak’s Engkari River in Malaysian Borneo\, along with twenty-one other communities and a land area of 8500 ha disappeared because of the building of the Batang Ai Hydroelectric Dam and the creation of a 33 sq mile reservoir. With the drowning of these houses\, lands\, forests\, and of multiple rivers and streams\, the history of one of the longest-occupied and most historically rich Iban territories in Sarawak was gone. Many of the 3000 people who were displaced moved to government-created resettlement areas. Some left for other parts of Sarawak\, and their descendants scattered around the world. All of those who were forced to leave their Batang Ai and Engkari homelands found their livelihoods completely transformed; none were free to pursue the rice agriculture and forest- and river-centered lives that they had known since their childhoods. \nThree decades after this event\, the ex-residents and descendants of Nanga Jela engaged in a process of reconstructing that submerged history and reconstituting an Engkari and Nanga Jela identity. Rescuing and sharing what images exist of the longhouse and its surrounding land- and waterscapes\, collecting oral histories\, geographical memories\, genealogies\, and a plethora of other local data\, and employing multiple social media tools\, the increasingly diverse\, geographically dispersed community is regaining its history\, knowledge of the lost land- and riverscapes\, and its identity. \nA team comprising Bobby Anak Nyegang and Itin Anak Langit\, both born in Nanga Jela\, and Christine Padoch\, an anthropologist who spent more than two years in the longhouse\, led the effort to assemble these and other materials into an image-rich bilingual (English and Iban) book that would be accessible to all in the Nanga Jela community\, as well as a community-based archive. In this presentation\, Padoch will discuss that complex process of writing the book\, recently published as Pemulai ke NangaJela/Return to Nanga Jela and creating an archive together with the longhouse community to provide present and future descendants of the great longhouse on the Engkari River a written history of a landscape and a livelihood that has disappeared. \nAbout the Speakers:  \nChristine Padoch is a Senior Curator Emerita in the Center for Plants\, People and Culture of the New York Botanical Garden. From 2011 to 2017 she was the Director of Research on Forests and Human Well-Being at the Center for International Forestry Research (CIFOR). An anthropologist by training\, she has spent about 50 years carrying out research on smallholder patterns of forest management\, agriculture\, and agroforestry in the humid tropics\, principally in Southeast Asia and Amazonia. Previous to her position at CIFOR\, Padoch was the Matthew Calbraith Perry Curator of Economic Botany at the NYBG. She is the author or editor of a dozen books and of approximately 100 scientific articles and book chapters. Christine Padoch has served as a scientific advisor to many international projects and has been a member of the boards of several international research institutions\, including the Center for International Forestry Research (CIFOR)\, the Amazon Institute for Environmental Research (IPAM)\, and the Earth Innovation Institute (EII). She holds a Ph.D. from Columbia University. \nNancy Lee Peluso is Professor of Environmental Social Science and Resource Policy in the College of Natural Resources and the Program Director of the Berkeley Workshop in Environmental Politics\, housed in the Institute of International Studies. She serves as a faculty member in the Society and Environment Division of the Department of Environmental Science\, Policy and Management\, where she teaches courses in Political Ecology. Her research since the 1980s has focused on Forest Politics and Agrarian Change in Southeast Asia\, primarily in Indonesia. She has done field research in various parts of Indonesia—West and Central Java\, East and West Kalimantan and in Sarawak\, Malaysia. Her work addresses questions of property rights and access to resources\, forest policy and politics\, histories of land use change\, and agrarian and environmental violence. She is the author or editor of three books: Rich Forests\, Poor People: Resource Control and Resistance in Java (UC Press\, 1992 – still available); Borneo in Transition: People\, Forests\, Conservation and Development (Oxford Press\, 1996 and 2003\, ed. with Christine Padoch); and Violent Environments (Cornell Press\, 2001\, ed. with Michael Watts.)\, and nearly fifty journal articles and book chapters. Professor Peluso speaks or reads four languages besides English. In 2003\, she was awarded a Harry Frank Guggenheim Fellowship and is finishing a book manuscript tentatively titled\, “Ways of Seeing Borneo: Landscape\, Territory\, and Violence”. She is currently working on a comparative study on the formation of “political forests” in Malaysia\, Indonesia\, and Thailand as well as a book examining the entanglements of violence and territoriality in landscape history in West Kalimantan.
URL:https://events.ucsc.edu/event/pemulai-ke-nanga-jela-return-to-nanga-jela/
LOCATION:Humanities 1 Building\, 257 Cowell-Stevenson Road\, Santa Cruz\, CA\, 95064\, United States
CATEGORIES:Lectures & Presentations
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DTSTART;TZID=America/Los_Angeles:20251204T134000
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SUMMARY:Behavioral\, Econometrics and Theory Seminar Series Presents: Jacopo Magnani
DESCRIPTION:Economics Behavioral\, Econometrics\, & Theory Seminar\nDate: Thursday\, December 4\, 2025\nTime: 1:40-3:00 p.m.\nLocation: E2-499\n\n \n\nSpeaker: Jacopo Magnani \nTitle:  Associate Professor of Economics \nAffiliation: Norwegian University of Science and Technology\, visiting Caltech\nHost: Kristian Lopez Vargas\n \nSeminar title: Behavioral Limits to Complete Markets\n \nABSTRACT:  Standard economic theory predicts that individuals should prefer complete markets to incomplete markets\, as the former allow state-contingent claims for every possible outcome. Yet real-world markets remain incomplete\, and the demand-side origins of the phenomenon are poorly understood. We develop an experimental framework to examine whether investors may themselves prefer incomplete markets\, and highlight two potential mechanisms: preference instability\, which exposes agents to greater regret or temptation in complete markets\, and complexity costs\, which arise because higher dimensionality increases cognitive effort and errors. In our experiment\, participants consistently reveal a preference for in complete markets\, contradicting the rational benchmark. Comparing homegrown and induced-preference treatments\, we find no evidence that this behavior is driven by preference instability. Instead\, utility losses\, response times\, and subjective ratings indicate that complexity costs drive the preference for incompleteness. Structural estimation confirms that complete markets are several times more complex than incomplete ones\, providing a behavioral foundation for market incompleteness. 
URL:https://events.ucsc.edu/event/behavioral-econometrics-and-theory-seminar-series-presents-jacopo-magnani/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Seminars
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DTSTART;TZID=America/Los_Angeles:20251204T180000
DTEND;TZID=America/Los_Angeles:20251204T190000
DTSTAMP:20260519T151211
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SUMMARY:Future careers: What will work look like in 2030?
DESCRIPTION:Join Dean PK Agarwal for this free online session. He’ll lead a forward-looking conversation on emerging job roles in tech\, sustainability\, health\, and creative industries. Learn how industry convergence and global trends are shaping new career paths and the skills you’ll need to stay relevant. \n\nDiscover which industries are driving job creation and how roles are evolving across tech\, sustainability\, health\, and the creative economy.\nUnderstand the impact of global trends—like AI\, climate change\, and demographic shifts—on the future of work.\nIdentify the skills and mindsets that will help you stay competitive and adaptable in a rapidly changing landscape.\n\nThis session is part of Pathways to Professional Success\, a new conversation series hosted by Dean P.K. Agarwal. \n\nClaim your seat!
URL:https://events.ucsc.edu/event/future-careers-what-will-work-look-like-in-2030/
LOCATION:Silicon Valley Campus\, 3175 Bowers Avenue\, Santa Clara\, CA\, 95054\, United States
CATEGORIES:Lectures & Presentations,Meetings & Conferences,Training
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DTSTART;TZID=America/Los_Angeles:20251204T180000
DTEND;TZID=America/Los_Angeles:20251204T190000
DTSTAMP:20260519T151211
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SUMMARY:Embedded Systems Program Info Session
DESCRIPTION:Build Your Career in Embedded Systems \nWhile hiring has slowed in some tech sectors\, the demand for skilled Embedded Systems professionals continues to grow across industries. \nAt this free winter info session\, you’ll learn about emerging roles in embedded technology and the essential skills that make your resume stand out. Discover how AI is being integrated into embedded systems—and how you can stay ahead of the curve with UCSC Silicon Valley Extension’s industry-aligned courses and expert instructors. \nFeatured Speaker:\nMichael Wang\, Chair of the UCSC Silicon Valley Extension Embedded Systems Certificate Program\, will share insights on the evolving job market\, key technical competencies\, and strategies to advance your career. \nThis session will also highlight two upcoming Winter courses ideal for building your foundation or deepening your expertise in Embedded Systems. \nThis winter info session is sponsored by the UCSC Silicon Valley Extension Embedded Systems certificate program. \n\nRegister today.
URL:https://events.ucsc.edu/event/embedded-systems-program-info-session/
LOCATION:Silicon Valley Campus\, 3175 Bowers Avenue\, Santa Clara\, CA\, 95054\, United States
CATEGORIES:Lectures & Presentations,Meetings & Conferences,Training
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