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DTSTART;TZID=America/Los_Angeles:20260817T100000
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DTSTAMP:20260810T162940Z
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UID:10015328-1786960800-1786968000@events.ucsc.edu
SUMMARY:Nikolakakis\, M. (ECE) - Learned Gridless Representations of Cone Beam Computed Tomography Scans
DESCRIPTION:Medical image representation has long been dominated by voxel-grid matrices. While\ntheir inherent structure and order work efficiently for various linear transformations and\nprovide a seamless visualization method on monitors\, they fail to preserve the topology\nof the scan and to encode sparse information in a memory-efficient way.   The recent emergence of machine learning-based continuous coordinate-based\nscene representations such as neural radiance fields and Gaussian splatting has provided alternative representation techniques. These approaches overfit the weights of\na model by iterative differentiable rendering and have been shown to be more compact than grid representations. They are then able to perform novel view\nsynthesis from any given camera pose.\nOff-grid representations translate directly to Cone Beam Computed Tomography\nsparse-view acquisitions\, where streaking and quantum noise artifacts are dominant.\nUsing differentiable rendering\, a continuous representation is achieved\, with interpolation providing a path to recover some of the lost signal.\nIn this dissertation\, we apply a variety of methodologies\, including Gaussian splatting\, implicit occupancy fields\, and Neural Attenuation Fields regularized with an\nanatomic prior\, to Cone Beam Computed Tomography reconstruction\, and evaluate\ntheir performance across a range of anatomic datasets. Our models show that learned\ngridless representations achieve substantial memory reduction\, recover signal under\nextreme view sparsity\, and preserve scene topology. \nEvent Host: Manolis Nikolakakis\, Ph.D. Candidate\, Electrical and Computer Engineering  \nAdvisor: Razvan Marinescu \nZoom: https://ucsc.zoom.us/j/5964517596?pwd=c1AwRlJLNk5pVzFBUENibEw3by85Zz09
URL:https://events.ucsc.edu/event/nikolakakis-m-ece-learned-gridless-representations-of-cone-beam-computed-tomography-scans/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Ph.D. Presentations
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DTSTART;TZID=America/Los_Angeles:20260817T130000
DTEND;TZID=America/Los_Angeles:20260817T150000
DTSTAMP:20260813T194341Z
CREATED:20260813T194341Z
LAST-MODIFIED:20260813T194341Z
UID:10015338-1786971600-1786978800@events.ucsc.edu
SUMMARY:Condon\, C. (BMEB) - Genomic conflict across scales
DESCRIPTION:Genomes are often viewed as cooperative systems in which genes work together to support organismal function. Yet genetic elements can also act in ways that favor their own transmission or persistence\, creating conflict within the genome. In this talk\, I examine the evolutionary and functional consequences of such genomic conflict across three systems. First\, I investigate segregation distortion in Arabidopsis hybrids and its potential role in the early evolution of reproductive isolation. Second\, I characterize the population dynamics and functional effects of introners\, mobile elements that generate new introns in the green alga Micromonas pusilla. Finally\, I explore widespread splicing dysfunction in algal mating-type chromosomes and its consequences for transcript diversity. Together\, these studies highlight how departures from genome cooperation can shape inheritance\, genome evolution\, and gene regulation. \nEvent Host: Chris Condon\, Ph.D. Candidate\, Biomolecular Engineering & Bioinformatics  \nAdvisor: Russell Corbett-Detig
URL:https://events.ucsc.edu/event/condon-c-bmeb-genomic-conflict-across-scales/
LOCATION:Biomedical Sciences Building\, 575 McLaughlin Drive
CATEGORIES:Ph.D. Presentations
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