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DTSTART;TZID=America/Los_Angeles:20251106T114000
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SUMMARY:BME 280B Seminar: Anne Nakamoto\, Alan Zhang\, Shelbi Russell
DESCRIPTION:Presenter 1: Anne Nakamoto\, BME PhD Candidate\, Corbett-Detig Lab\, UC Santa Cruz \nTalk: Investigating deleterious mutation burden across populations and landscapes in the California Conservation Genomics Project \nDescription: Biodiversity is being lost at an accelerated rate due in part to anthropogenic forces\, posing a threat to the sustainability of Earth’s ecosystems as well as to human health. A major goal of conservation genomics is to use genomic data to understand population health\, which can inform management decisions for the preservation of biodiversity. The California Conservation Genomics Project (CCGP) is an extensive dataset containing species of conservation interest sampled across California\, allowing a landscape genomics approach to conservation. Among the many metrics that can be used to assess population health is genetic load\, which refers to the reduction in fitness imposed by deleterious mutations. In this work\, we construct a bioinformatic analysis framework to identify deleterious genomic variants in CCGP species based on evolutionary constraint. This allows us to investigate patterns in genetic burden across populations and the landscape of California. \nPresenter 2: Alan Zhang\, BME PhD Candidate\, Corbett-Detig Lab\, UC Santa Cruz \nTalk: Scalable Strain-Level Metagenomic Deconvolution and Assembly Using Pangenome Mutation-Annotated Networks \nDescription: Strain-level deconvolution of metagenomic samples is essential for pathogen surveillance\, mixed infection diagnosis\, and evolutionary genomics\, yet remains computationally challenging as genomic databases expand. Existing methods scale poorly with database size or rely exclusively on single nucleotide polymorphism (SNP) information. SNP-based approaches rely on mutation-annotated trees and thus require well-established reference genomes\, limiting their applicability to divergent species that lack alignable root references. We present panMAMA (panMAN Metagenomic Assignment and Metagenomic Assembly)\, a method that leverages the pangenome Mutation-Annotated Network (panMAN) data structure to enable accurate strain-level quantification across both closely related and divergent genomes. By employing k-min-mer-based pseudo-chaining with a seed-annotated tree index\, panMAMA achieves substantial computational speedup compared to existing k-mer-based tools while maintaining high accuracy. We demonstrate that panMAMA accurately deconvolves both closely related SARS-CoV-2 genomes and divergent HIV and respiratory syncytial virus (RSV) genomes\, outperforming existing tools including Freyja on simulated wastewater samples. Through a hybrid heuristic and maximum likelihood approach for read assignment and consensus calling\, panMAMA effectively recovers variant genomes from low-heterogeneity samples of divergent species. These results establish panMAMA as a scalable and accurate platform that extends strain-level metagenomic analysis to previously intractable highly divergent species. \nPresenter 3: Shelbi Russell\, PhD\, UC Santa Cruz\, Ph.D.\, Organismic & Evol Bio\, Harvard\, PostDoc MCDB\, UC Santa Cruz \nDescription: Many animals harbor bacterial symbionts that manipulate host reproduction to enhance bacterial survival and transmission. Obligate intracellular symbionts\, such as Wolbachia pipientis\, are particularly adept at host manipulation\, influencing reproductive biology and even blocking viral replication. These bacterially induced traits have been harnessed in field studies to control mosquito populations and limit the spread of human pathogens like Dengue and Zika viruses. Despite these promising applications\, the molecular mechanisms underlying Wolbachia’s interactions with host cells remain poorly understood. Furthermore\, even less is known about the implications of these symbionts spreading to non-target hosts in the ecosystem. Previous work from my lab tackled these questions in vivo: we discovered that the wMel strain of Wolbachia can enhance host fertility and we discovered that even extremely low rates of horizontal symbiont transmission among hosts can influence bacterial genome evolution. However\, in vivo systems offer limited resolution to identify the precise cellular mechanisms of fertility enhancement and the real-time genomic impacts of horizontal transmission. Here\, we use an in vitro Drosophila system to 1) identify the cell type-specific impacts of Wolbachia infection on host-microbe interactions and 2) characterize how strains interact within host tissues during mixed infections. This simplified\, easy to sample system enabled us to concentrate the effects of host cell type on Wolbachia gene expression and to control de novo strain infections and mixtures. Through these experiments\, we discovered that different host cell types induce differential Wolbachia gene expression that feeds back to alter host gene expression and epigenetic silencing. These findings have motivated on-going single cell RNAseq work to resolve the process at the single cell level\, during de novo infections. Results from the experimental mixed infections revealed highly reproducible strain and cell type-specific dynamics. We will leverage these discoveries to understand strain-specific tissue tropisms and how multiple strains can co-exist as superinfections in nature\, which will inform future biocontrol strategies. \nBio: Shelbi is an Assistant Professor in the Department of Biomolecular Engineering at UCSC. She started her lab in 2022\, after completing her PhD at Harvard University in 2016 and performing her postdoctoral work at UCSC. Her passion for studying symbiotic systems began as an undergraduate researcher at the University of Kansas describing new tapeworm species. She transitioned to studying the evolutionary genomics of bacterial-animal mutualisms in her PhD and was awarded the UC Chancellor’s Postdoctoral Fellowship and the NIH Career Development Award (K99) to test genomic hypotheses in the Wolbachia-Drosophila model system during her postdoc. As faculty\, she is working to learn how hosts and microbes function and evolve so we can engineer associations for biological control. She has authored 24 papers and obtained $2.75 million in funding. Her interdisciplinary training makes her uniquely qualified to lead these investigations and has enabled novel breakthroughs in our understanding of symbiont evolution and microbe-induced host phenotypes. \nHosted by: Professor Josh Stuart\, BME Department \nRoom: PSB-240
URL:https://events.ucsc.edu/event/bme-280b-seminar-anne-nakamoto-alan-zhang-shelbi-russell/
LOCATION:Physical Sciences Building\, Physical Sciences Building\, Santa Cruz\, CA\, 95064
CATEGORIES:Lectures & Presentations,Seminars
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DTSTART;TZID=America/Los_Angeles:20251106T134000
DTEND;TZID=America/Los_Angeles:20251106T150000
DTSTAMP:20260422T210535
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SUMMARY:Applied Microeconomics and Trade Seminar Series presents: Matt Pecenco
DESCRIPTION:Applied Microeconomics and Trade Seminar\nDate: Thursday\, November 6\, 2025\nTime: 1:40-3:00 p.m.\nLocation: E2-499\n\n \n\nSpeaker: Matt Pecenco\nTitle: Orlando Bravo Assistant Professor of Economics \nAffiliation: Brown University \nHost: Ariel Zucker \n \nSeminar title: Conviction\, Incarceration\, and Policy Effects in the Criminal Justice System\n \nABSTRACT:   The criminal justice system affects millions of Americans through criminal convictions and incarceration. In this paper\, we introduce a new method for credibly estimating the effects of both conviction and incarceration using randomly assigned judges as instruments for treatment. Misdemeanor convictions\, especially for defendants with a shorter criminal record\, cause an increase in the number of new offenses committed over the following five years. Incarceration on more serious felony charges\, in contrast\, reduces recidivism during the period of incapacitation\, but has no effect after release. Our method allows the researcher to isolate specific treatment effects of interest as well as estimate the effect of broader policies; we find that courts could reduce crime by dismissing marginal charges against defendants accused of misdemeanors\, with larger reductions among first-time defendants and those facing more serious charges.
URL:https://events.ucsc.edu/event/applied-microeconomics-and-trade-seminar-series-presents-matt-pecenco/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Seminars
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251113T134000
DTEND;TZID=America/Los_Angeles:20251113T150000
DTSTAMP:20260422T210535
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SUMMARY:Applied Microeconomics and Trade Seminar Series presents: Giovanni Peri
DESCRIPTION:Applied Microeconomics and Trade Seminar\nDate: Thursday\, November 13\, 2025\nTime: 1:40-3:00 p.m.\nLocation: E2-499\n\n \n\nSpeaker: Giovanni Peri\nTitle: C. Bryan Cameron Distinguished Professor in International Economics \nAffiliation: UC Davis\nHost: Gueyon Kim\n \nSeminar title: How the1942 Japanese Exclusion Impacted U.S. Agriculture\n \nABSTRACT:  In the early 1940s\, Japanese American farmers and farm workers represented an important part of agriculture-specific human capital in the United States. In 1942 all those living in the “exclusion zone” along the WestCoastwereforcefully relocated to internment camps and most of them never returned to farming. Using county-level panel data from historical agricultural censuses and a triple-difference (DDD) estimation approach we find that\, by 1960\, counties in the exclusion zone experienced 12% lower cumulative growth in farm value for each percentage point loss of their 1940 share of Japanese farm workers\, relative to counties outside the exclusion zone. Farm revenues\, farm productivity\, adoption of high-value crops\, mechanization\, and farm wages were also correspondingly lower. Taken together\, these findings are consistent with Japanese farmers representing hard-to-replace human capital\, rather than replaceable labor\, in US agriculture.
URL:https://events.ucsc.edu/event/applied-microeconomics-and-trade-seminar-series-presents-giovanni-peri/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Seminars
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251117T104000
DTEND;TZID=America/Los_Angeles:20251117T114500
DTSTAMP:20260422T210535
CREATED:20251113T000837Z
LAST-MODIFIED:20251113T000837Z
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SUMMARY:ECE 290 Seminar: Low-Power and Miniaturized Medical Electronics for in vivo Localization and Tracking
DESCRIPTION:Presenter: Dr. Saransh Sharma\, Postdoctoral Scholar\, MIT \nDescription: Accurate in vivo localization of medical devices is central to applications ranging from ingestible pills in the GI tract to endovascular and minimally invasive procedures. However\, current clinical methods rely on endoscopy or repeated ionizing imaging (CT/X-ray)\, and are poorly suited for continuous or out-of-hospital use. In this talk\, I will present a radiation-free platform for high-precision localization of wireless miniaturized devices in vivo\, using engineered magnetic field gradients. We design battery-less ingestible microdevices that measure and transmit their local magnetic field\, while planar coils generate monotonically varying fields in X\, Y\, and Z. This architecture uniquely encodes spatial position and achieves <100 μm 3D accuracy—to our knowledge\, the highest reported. We then translate this to in vivo large-animal studies to localize ingestible devices in the GI tract in real time with mm-scale resolution\, without radiation or hospital-grade imaging. This enables continuous monitoring relevant to constipation\, incontinence\, motility disorders\, medication adherence\, and quantitative GI transit-time. Next\, I will show how this platform generalizes to surgical navigation. By embedding the same localization architecture into catheters and guidewires\, we can track device position without fluoroscopy\, offering a pathway toward image-free vascular navigation and minimally invasive interventions. Finally\, to further shrink devices and power\, I developed a monolithic 3D magnetic sensor in 65 nm CMOS (4 mm²\, 14.8 μW\, <10 μT_rms noise). This fully CMOS-compatible architecture enables high-sensitivity magnetic sensing at μW power\, and can serve as the core for future miniaturized\, radiation-free localization systems. \nBio: Dr. Saransh Sharma received the B.Tech. degree in Electronics and Electrical Communication Engineering from the Indian Institute of Technology (IIT)\, Kharagpur\, India\, in 2017\, and the M.S. and Ph.D. degrees in Electrical Engineering from the California Institute of Technology (Caltech)\, Pasadena\, CA\, USA\, in 2018 and 2023\, respectively. He is currently a postdoctoral research scholar at the Massachusetts Institute of Technology (MIT)\, Cambridge\, USA\, working on low-power analog and mixed-signal integrated circuits and system design for bio-medical applications. Dr. Sharma was a recipient of the Wilts Prize and the Demetriades-Tsafka-Kokkalis Award for outstanding Ph.D. thesis in Electrical Engineering\, Biotechnology and related fields at Caltech\, Lewis Winner Award for outstanding paper at ISSCC 2024\, Best Student Paper Award at CICC 2025\, Charles Lee Powell Fellowship at Caltech\, and Excellence in Mentorship Award at Caltech for mentoring undergraduate and graduate students. \nHosted by: Professor Soumya Bose\, ECE Department \nZoom Link: https://ucsc.zoom.us/j/97975378707?pwd=ljcgaCfhMmhZ88Vt5dqQUBVQRjehOx.1
URL:https://events.ucsc.edu/event/ece-290-seminar-low-power-and-miniaturized-medical-electronics-for-in-vivo-localization-and-tracking/
LOCATION:CA
CATEGORIES:Lectures & Presentations,Seminars
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251117T120000
DTEND;TZID=America/Los_Angeles:20251117T130000
DTSTAMP:20260422T210535
CREATED:20251124T181658Z
LAST-MODIFIED:20251124T181658Z
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SUMMARY:Global Learning Alumni Panel: Study Abroad & Away Experiences
DESCRIPTION:Have you ever wondered what it’s like to study abroad or participate in a domestic study away program?  \nJoin us for a virtual alumni panel where past participants of global learning programs will share their unique experiences\, personal stories\, and advice for making the most of your journey. This is your chance to ask questions\, get inspired\, and connect with alumni who have been where you’re headed. Don’t miss out! \nRegister here for the Global Learning Alumni Panel \nDate: Monday\, November 17 \nTime: 12:00 – 13:00 \nLocation: Zoom \nThis event is part of UCSC’s International Education Week. If you have any questions\, please contact us at globallearning@ucsc.edu.
URL:https://events.ucsc.edu/event/global-learning-alumni-panel-study-abroad-away-experiences/
LOCATION:CA
CATEGORIES:Lectures & Presentations,Seminars,Social Gathering,Workshop
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251117T123000
DTEND;TZID=America/Los_Angeles:20251117T133000
DTSTAMP:20260422T210535
CREATED:20251106T184902Z
LAST-MODIFIED:20251106T185358Z
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SUMMARY:CM Seminar: "Playful Design to Empower Climate Adaptation - What are we missing for real-life impact?"
DESCRIPTION:Presented by: Linda Hirsch \n  \nDescription: “Games and playful interventions have been researched to increase awareness of climate change impacts and educate about mitigation and adaptation measures. However\, besides increased awareness\, what real-life impact and adapted behaviors can we actually observe from such interventions? In this talk\, I will reflect on the differences between short-term and long-term community empowerment through playful interventions and discuss three outstanding research directions for designing real-life climate adaptation.” \nBio: Linda Hirsch is a postdoctoral researcher at Computational Media\, UCSC\, under the supervision of Katherine Isbister. She holds a magna cum laude doctoral degree in Media Informatics from LMU Munich\, Germany. Her research focuses on exploring\, conceptualizing\, and creating meaningful human-environment interactions to strengthen communities toward increased climate resilience. Linda Hirsch has been an elected executive committee member of the German group “Be-greifbare Interaktion” since 2021\, an expert research group within the German Society of Information Technology regarding topics for tangible and embedded interfaces.  \n  \nHosted by: Professor Katherine Isbister \nWhen: Monday\, November 17\, 2025 from 12:30PM to 1:30PM \nLocation:  \nIN-PERSON @ UCSC Main Campus\, E2-280. \nViewing room @ SVC 3212.  \nLUNCH WILL BE PROVIDED AT BOTH LOCATIONS! Faculty and students are highly encouraged to attend. \n  \nZoom info:  \nhttps://ucsc.zoom.us/j/97750591512?pwd=YLpfQyb9rQCAJaxBSWqO5vVzajdD3r.1 \nMeeting ID: 977 5059 1512\nPasscode: 039229
URL:https://events.ucsc.edu/event/cm-seminar-playful-design-to-empower-climate-adaptation-what-are-we-missing-for-real-life-impact/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Lectures & Presentations,Seminars
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251118T134000
DTEND;TZID=America/Los_Angeles:20251118T150000
DTSTAMP:20260422T210535
CREATED:20251107T004436Z
LAST-MODIFIED:20251120T171912Z
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SUMMARY:Macroeconomics & International Finance Seminar Series Presents: Yuriy Gorodnichenko
DESCRIPTION:Macroeconomics and International Finance Seminar\nDate: Tuesday\, November 18\, 2025\nTime: 1:40-3:00 p.m.\nLocation: E2-499\n\n \n\nSpeaker: Yuriy Gorodnichenko\nTitle: Quantedge Presidential Professor of Economics\nAffiliation: UC Berkeley\nHost: Pascal Michaillat\n \nSeminar title:  How costly are business cycle volatility and inflation? A Vox Populi approach\n \nABSTRACT:  Using surveys of households across thirteen countries\, we study how much individuals would be willing to pay to eliminate business cycles. These direct estimates are much higher than traditional measures following Lucas (2003): on average\, households would be prepared to sacrifice around 5-6% of their lifetime consumption eliminate business cycle fluctuations. A similar result holds for inflation: to bring inflation to their desired rate\, individuals would be willing to sacrifice around 5% of their consumption. Willingness to pay to eliminate business cycles and inflation is generally higher for those whose consumption is more pro-cyclical\, those who are more uncertain about the economic outlook\, and those who live in countries with greater historical volatility. 
URL:https://events.ucsc.edu/event/macroeconomics-international-finance-seminar-series-presents-yuriy-gorodnichenko/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Seminars
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251124T104000
DTEND;TZID=America/Los_Angeles:20251124T114500
DTSTAMP:20260422T210535
CREATED:20251117T231136Z
LAST-MODIFIED:20251117T231136Z
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SUMMARY:ECE 290 Seminar: Fundamental Nanopower Analog Circuits
DESCRIPTION:Presenter: Joey Sankman\, Analog/Power Designer\, Analog Devices \nDescription: With the rising interest in edge computing\, and the addition of AI/ML functionality\, nanopower circuits are in great demand to reduce the quiescent power consumption of remote sensors. In this tutorial\, fundamental building blocks for nanopower circuits will be covered\, including startup-less low-voltage references\, low-frequency clocks\, and LDO regulators. Attendees can expect a deep dive into fundamental and practical analog techniques to design nanopower systems. \nBio: Joey Sankman received the B.S. degree from the University of Arizona\, Tucson\, AZ\, and Ph.D. degree from the University of Texas at Dallas\, TX in electrical engineering in 2010 and 2014\, respectively. At the University of Texas at Dallas\, his research included energy harvesting circuits and systems as well as high-performance switch mode power converters. He is currently an analog/power designer at Analog Devices\, Principal Member of Technical Staff\, working on automotive PMICs. Previously\, he was an Analog R&D Engineer working on audio amplifiers\, ultra-low power circuits\, and radhard gate drivers at Kilby Labs\, TI\, Dallas\, TX. He was the recipient of the U.S. National Science Foundation Graduate Research Fellowship and the 2011 Texas Instruments/Semiconductor Research Corporation Graduate Fellowship. He has authored or co-authored 20 publications in various IEEE journals and conferences. He currently serves on the IEEE ISSCC power subcommittee. \nHosted by: Professor Soumya Bose\, ECE Department \nZoom Link: https://ucsc.zoom.us/j/97975378707?pwd=ljcgaCfhMmhZ88Vt5dqQUBVQRjehOx.1
URL:https://events.ucsc.edu/event/ece-290-seminar-fundamental-nanopower-analog-circuits/
LOCATION:CA
CATEGORIES:Lectures & Presentations,Seminars
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251124T160000
DTEND;TZID=America/Los_Angeles:20251124T170000
DTSTAMP:20260422T210535
CREATED:20251105T172921Z
LAST-MODIFIED:20251105T172921Z
UID:10005096-1764000000-1764003600@events.ucsc.edu
SUMMARY:AM Seminar: Linear Stochastic Emulators of the Ocean Circulation based on Balanced Truncation: A Caution\, perhaps\, for Machine Learning?
DESCRIPTION:Presenter: Professor Andy Moore\, UCSC Ocean Sciences \nDescription: Linear inverse models have enjoyed considerable popularity in the geosciences\, particularly in the arena of climate research and climate prediction\, for several decades as a straightforward approach to dimension reduction and streamlining computational efficiency. The most common approach is to truncate the system by retaining the leading Empirical Orthogonal Functions (EOFs) which represent the left singular vectors of the transition matrix. While singular value decomposition is the best low rank approximation of the transition matrix\, ignoring information contained in the right singular vectors\, as is commonly done in linear inverse models\, has consequences for the dynamics that approximate the system. Dimension reduction based on balanced truncation simultaneously preserves information from the right and left singular vectors. This talk will review some of these ideas and present examples from the ocean. Since EOF decomposition is quite commonly used for dimension reduction in some machine learning approaches\, there may be some lessons here for the machine learning community to consider. \nBio: Professor at UCSC since 2016. \nHosted by: Professor Julie Simons
URL:https://events.ucsc.edu/event/am-seminar-linear-stochastic-emulators-of-the-ocean-circulation-based-on-balanced-truncation-a-caution-perhaps-for-machine-learning/
LOCATION:CA
CATEGORIES:Lectures & Presentations,Seminars
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20251125T134000
DTEND;TZID=America/Los_Angeles:20251125T150000
DTSTAMP:20260422T210535
CREATED:20251108T002503Z
LAST-MODIFIED:20251120T174503Z
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SUMMARY:Macroeconomics & International Finance Seminar Series Presents: Helen Popper
DESCRIPTION:Macroeconomics and International Finance Seminar\nDate: Tuesday\, November 25\, 2025\nTime: 1:40-3:00 p.m.\nLocation: E2-499\n\n \n\nSpeaker: Helen Popper\nTitle: Professor of Economics\nAffiliation: Santa Clara University \nHost: Galina Hale\n \nSeminar title:  Artificial Intelligence and Macroeconomic Dynamics: Growth\, Pricing\, and Distribution\n \nABSTRACT:  This paper builds a simple general equilibrium model in which an AI producer is a monopolist who both learns by doing and uses AI recursively as an input. These mechanisms link today’s scale to tomorrow’s costs\, so pricing is dynamic: the firm sets a price below the static monopoly benchmark to expand capacity and speed learning. Final goods are produced by monopolistic competitors with constant returns to scale each period. We first use Cobb–Douglas technologies to solve for a generalized balanced growth path that pins down the condition for stable\, nonexplosive growth. On this path\, AI output grows faster than final output\, the relative price of AI falls persistently\, real wages rise with overall output\, and the specialized–to–nonspecialized wage ratio is flat. We then analyze CES versions of both sectors and derive a closed form effective demand elasticity for AI that combines input substitution in production with final-goods market substitution across varieties. Finally\, simulations link adoption and distribution to elasticities\, and they allow us to explore the dynamics. When final-goods inputs are complements\, adoption is learning-first and capital-light before scaling; when they are substitutes\, adoption is scale-first and the two-phase pattern attenuates. On the distribution side\, the specialized–to–nonspecialized wage premium is lowest with complements and rises with substitutes. Greater substitutability in AI production amplifies these patterns without changing their sign.
URL:https://events.ucsc.edu/event/macroeconomics-international-finance-seminar-series-presents-helen-popper/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Seminars
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