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DTSTART;TZID=America/Los_Angeles:20250811T183000
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DTSTAMP:20260417T070010
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SUMMARY:August Slugs & Steins with Professor Nancy N. Chen
DESCRIPTION:Breathing in the Anthropocene: Reflections on Breath\, Air\, and Vitality \nThis presentation examines breathing in the present moment when humans vastly transform Earth ecosystems that impact health and well-being. Atmospheric transformations via worsened air highlight connections of breath with health. How might breath be shaped by cultural and individual experiences? Ethnographic research at the intersections of medical and environmental anthropology have renewed attention on energetic relations between bodies\, landscapes\, air\, and health\, especially the role of vital energy in qi\, prana\, or ha. In addition to these breath centered approaches\, we examine recent biomedical research on breath management across a broad range of complementary medicine and health interventions.
URL:https://events.ucsc.edu/event/august-slugs-steins-with-professor-nancy-n-chen/
LOCATION:CA
CATEGORIES:Lectures & Presentations
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250812T120000
DTEND;TZID=America/Los_Angeles:20250812T120000
DTSTAMP:20260417T070010
CREATED:20250808T070000Z
LAST-MODIFIED:20250925T231429Z
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SUMMARY:BME Special Seminar: La protein and the RNA Polymerase III transcriptome
DESCRIPTION:Presenter: Richard J Maraia\, MD\, Senior Investigator and Head of the Section on Molecular and Cell Biology in the Intramural Research Program\, NICHD \nDescription: The La protein is a eukaryote-ubiquitous RNA-binding protein that (in the organisms examined) stabilizes newly synthesized RNA polymerase (Pol) III transcripts by transiently protecting their 3’-ends prior to maturation as abundant stable noncoding (nc)RNAs. While Bacteria and archaea use a single RNA polymerase to produce their cellular RNAs\, Pol III is specialized to synthesize short RNAs in large amounts\, e.g.\, tRNAs at >10-fold molar levels relative to ribosomal RNA synthesized by Pol I. tRNA genes are the most numerous of Pol III-transcribed genes\, followed by 5S rRNA and a few single-to-low copy noncoding (nc)RNA genes. The numbers of tRNA genes have been expansive and dynamic in eukaryotes\, presumably facilitated by their “internal split promoter” (A-box and B-box) which roughly correspond to the most conserved regions of tRNAs\, the D and T loops. The Pol III-specific transcription factor\, TFIIIC binds to this promoter and directs transcription at the upstream initiation site\, i.e.\, even if the tRNA sequence is inserted at a different locus. Transcription termination by Pol III is by a unique mechanism\, directed by its second largest subunit\, RPC2 which together with help of another Pol III-specific subunit reads the ≥4 consecutive Ts on the nontemplate strand as a pause signal that results in release the RNA. The first part of the talk will be on a paper under revision\, A POLR3B-variant reveals a RNA Polymerase III transcriptome response dependent on the SSB/La protein. In this study\, we performed extensive molecular characterization on a patient case that we found in the NIH Undiagnosed Disease Program (UDP) with homozygous SNPs in RPC2 and gained new insight as per the title. The second part of the talk will be related to a paper published in July 2025 that reflects diversity of tRNA genes. More specifically\, we discovered a tRNA gene with apparent latent noncanonical activity to activate cellular interferon signaling\, in addition to its mRNA decoding activity\, and characterized its features and those of a minority subset of other human tRNA genes that exhibit this activity from those in a majority that don’t. \nBio: Richard J. Maraia focuses on RNA polymerase III\, Genetics\, RNA\, Small nuclear RNA and RNA polymerase II. The study incorporates disciplines such as Inverted repeat\, Genomic organization\, Termination factor\, Molecular biology and Heterochromatin in addition to RNA polymerase III. His Molecular biology research incorporates elements of Apoptosis\, Mdm2\, Cancer research and Small interfering RNA. \nHis studies in RNA integrate themes in fields like Transcription and Protein biosynthesis. The concepts of his Small nuclear RNA study are interwoven with issues in RNase P and RNA recognition motif. Richard J. Maraia has included themes like General transcription factor and DNA polymerase in his RNA polymerase II study. \nHe is the ongoing chair of the NIH RNA club and serves on the organizing committees of the international biennial conferences on RNA polymerases I & III and the biennial conferences on La and related protein (LARP). He served on the Earl Stadtman Investigator Search committees for Molecular Biology and Biochemistry as chair and for RNA Biology at the NIH. He had speciality training in pediatrics and interinstitute medical genetics at the NIH. \n\nHosted by: Professor Todd Lowe\, BME Department
URL:https://events.ucsc.edu/event/bme-special-seminar-la-protein-and-the-rna-polymerase-iii-transcriptome/
LOCATION:CA
CATEGORIES:Lectures & Presentations
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250812T173000
DTEND;TZID=America/Los_Angeles:20250812T173000
DTSTAMP:20260417T070010
CREATED:20250724T070000Z
LAST-MODIFIED:20250925T231319Z
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SUMMARY:Effective Multigenerational Communication
DESCRIPTION:Join the Silicon Valley NHRA and learning partner Steps for an interactive session using drama-based learning to improve communication across generations in the workplace. Through scenario-based activities\, you'll explore real-world challenges and uncover how different generations approach work\, communication\, and leadership. Learn how this approach supports HR and talent strategies by equipping teams with the tools to build stronger connections and a greater sense of belonging. Discover how generational differences can become a strength—not a barrier—to organizational success. \nThis event is sponsored by the UCSC Silicon Valley Extension Human Resource Management Certificate Program.
URL:https://events.ucsc.edu/event/effective-multigenerational-communication/
LOCATION:Silicon Valley Campus\, 3175 Bowers Avenue\, Santa Clara\, CA\, 95054\, United States
CATEGORIES:Lectures & Presentations,Meetings & Conferences,Training
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DTSTART;TZID=America/Los_Angeles:20250813T100000
DTEND;TZID=America/Los_Angeles:20250813T100000
DTSTAMP:20260417T070010
CREATED:20250805T070000Z
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SUMMARY:Interested in a paralegal career?
DESCRIPTION:You are invited to join a free\, online informational session to learn more about the Center for Legal Studies Paralegal Certificate Course©\, a professional education program taught through the UCSC Silicon Valley Extension Paralegal Studies program. \nTopics \n\n\nCareer growth and earning potential \n\n\nAn overview of how CLS works with accredited college and university partners \n\n\nCourse pricing and payment options \n\n\nCourse materials and textbooks \n\n\nInstructor and peer/student interactions \n\n\nHow the online course works \n\n\n\nQ&A: There will be 15 minutes dedicated to Q&A\, so please bring any questions you might have.  \nRegister to receive the event recording \nIf you are unable to attend the webinar at this date and time\, please still register and the BARBRI team will send out the recorded webinar for you to view. \nThis event is co-sponsored by the UCSC Silicon Valley Professional Education Legal Studies program.
URL:https://events.ucsc.edu/event/interested-in-a-paralegal-career-8312/
LOCATION:CA
CATEGORIES:Lectures & Presentations,Training
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250816T090000
DTEND;TZID=America/Los_Angeles:20250816T090000
DTSTAMP:20260417T070010
CREATED:20250610T070000Z
LAST-MODIFIED:20250925T231618Z
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SUMMARY:AI Workshop: Spiking Neural Networks
DESCRIPTION:Welcome to our immersive AI technology workshop series. During these sessions you will be introduced to new and established AI tools that will help you create and manipulate content in new and powerful ways. Each session is led by an industry expert who will guide you through the material and share its real-world implications. \nLearning Outcomes \nAt the conclusion of the workshop\, you should be able to \n\nDescribe and discuss the fundamental principles of Spiking Neural Networks (SNNs)\, including spike-based data representation\, key neuron models (e.g.\, Leaky Integrate-and-Fire)\, synaptic operations\, the current state-of-the-art in neuromorphic hardware\, and the realistic short-term and long-term potential of SNNs in the broader AI landscape.\nExplain the differences between Spiking Neural Networks (SNNs) and traditional Artificial Neural Networks (ANNs)\, articulating the motivational factors for SNN adoption such as energy efficiency and event-driven computation.\nDemonstrate an ability to properly and effectively implement simple SNN applications (e.g.\, the XOR problem and a more complex use case) using tools like Nengo\, understanding how information is encoded and processed through spike trains\, and applying different training approaches for SNNs while contrasting them with traditional backpropagation and evaluating the challenges and opportunities in SNN learning.\n\nTopics Include \n\nIntroduction to Spiking Neural Networks: What are SNNs? Visualizing spike-based computation.\nWhy SNNs Matter: Motivations (energy efficiency\, neuromorphic hardware)\, real-world applications (robotics\, IoT)\, and a realistic look at when they are most beneficial.\nCore Concepts of SNNs: Spike-based representation (events\, timing\, frequency)\, simplified neuron models (LIF)\, synaptic function\, and encoding strategies (rate vs. temporal).\nHands-On with SNNs (Nengo Demo): Interactive exploration of spike generation\, parameter tuning\, and visualizing network behavior.\nProblem Solving with SNNs:\nThe XOR problem: Understanding challenges with discrete logic.\nApplying SNNs to continuous\, real-world analog-like problems.\nTraining Spiking Neural Networks: Exploring alternatives to backpropagation (e.g.\, evolutionary computation\, PSO) and understanding the associated challenges.\nThe Neuromorphic Landscape: Introduction to key neuromorphic hardware (e.g.\, Intel Loihi\, BrainChip Akida)\, their architectures\, and real-world case studies.\nCurrent Limitations and Future Outlook: Discussing speed vs. efficiency\, challenges in tooling and frameworks\, and the short-term and long-term vision for SNN adoption.\n\nStudents are required to bring laptops for class exercises. \nThis event is co-sponsored by the UCSC Silicon Valley Professional Education Artificial Intelligence program.
URL:https://events.ucsc.edu/event/ai-workshop-spiking-neural-networks/
LOCATION:Silicon Valley Campus\, 3175 Bowers Avenue\, Santa Clara\, CA\, 95054\, United States
CATEGORIES:Lectures & Presentations,Meetings & Conferences,Training
GEO:37.3796975;-121.9765484
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