Leavitt, J. (BMEB) – Evolutionary Dynamics, Functional Adaptations in Stress Response, and Direct Detection of tRNA modifications in Archaea
Biomedical Sciences Building 575 McLaughlin DriveTransfer RNA (tRNA) modifications are essential for structural integrity, decoding fidelity, and stress adaptation, yet their dynamics across phylogenetically distinct archaeal species and their functional roles during stress remain incompletely understood. This dissertation aims to address some of these gaps through a multi-scale investigation that spans the evolutionary dynamics, stress-responsive functions, and direct detection of […]