Bai, G. (BMEB) – Long-read single-molecule chromatin architecture and its role in transcriptome regulation
Sequencing technologies have revolutionized our understanding of biology, yet many existing methods require fragmentation of DNA or RNA, fundamentally limiting our ability to study these molecules in their native, intact forms. Long-read sequencing overcomes this constraint by enabling the sequencing of long, single-molecule native DNA and RNA, providing simultaneous access to both sequence and base […]