Friends of the UCSC Farm & Garden Member Reception
2026-07-08 17:00 - 19:00 (America/Los_Angeles) | Hay Barn, 94 Ranch View Road, Santa Cruz, CA, 95064, United States
Current members of the Friends of the UCSC Farm & Garden are invited to our annual Member Reception in the Hay Barn on July 8. Learn about the Friends’ and the Center for Agroecology’s plans for the upcoming fiscal year while enjoying wine & beer, non-alcoholic beverages and hearty appetizers made with produce from the farm. Please RSVP for you and others in your party.
Learn about the Friends of the UCSC Farm & Garden and become a member

Spring Exhibitions at the Institute of the Arts and Sciences
2026-07-09 12:00 - 17:00, 2026-07-10 12:00 - 17:00, 2026-07-11 12:00 - 17:00, 2026-07-12 12:00 - 17:00, 2026-07-15 12:00 - 17:00, 2026-07-16 12:00 - 17:00, 2026-07-17 12:00 - 17:00 | Institute of the Arts and Sciences, 100 Panetta Ave, Santa Cruz, United States
Visit the IAS, UCSC’s premier art galleries, for our spring exhibitions. On view April 10–August 16, 2026 are three diverse and interdisciplinary shows: Libia Posada: Everything is Going Right, the first US solo exhibition by the Colombia-based artist and medical doctor; Gina Athena Ulysse: A Redwoods Rasanblaj, a site-specific and immersive exploration of the Haitian kreyol conception of rasanblaj; and Ronaldo V. Wilson: There Are No Words, But Melodies, a mixed-media exhibition emerging at the intersections of Black poetics, performance, and visual art.
The IAS Galleries are open Wednesday-Sunday, 12 pm – 5 pm. Admission is free to the public.
Libia Posada: Everything is Going Right
Libia Posada’s first solo exhibition in the United States features installations, sculptures, and drawings meticulously constructed from surgical instruments, gauze bandages, crutches, used books, and domestic picture frames. The new and existing works in the exhibition powerfully stitch together the personal, social, and political disorders and afflictions that currently trouble the world, from the wars that resonate across the globe to the violences of aging in US prisons.
Gina Athena Ulysse: A Redwoods Rasanblaj: Origins & Disentanglements
The internationally-lauded work of humanities professor Gina Athena Ulysse is on view as a premier Faculty Spotlight Exhibition. The site-specific installation, produced in community from things collected, found, purchased and donated, centers on the Haitian concept of rasanblaj, a form of assembly and collage that transcends the formal use of materials to draw together people, spirits, and ideas.
Ronaldo V. Wilson: There Are No Words, But Melodies
Collage is both a material practice and a structural interrogation in the Faculty Spotlight Exhibition artworks by literature professor Ronaldo V. Wilson. In video, painting, and installation, layers and folds conceal and reveal, delving into the experience, both bodily and emotive, of living in times of violence.

Visualizing Abolition Screening Series: Beyond Access
2026-07-09 12:00 - 17:00, 2026-07-11 12:00 - 17:00, 2026-07-12 12:00 - 17:00, 2026-07-15 12:00 - 17:00, 2026-07-16 12:00 - 17:00 | Institute of the Arts and Sciences, 100 Panetta Ave, Santa Cruz, United States
On view in the IAS Screening Room is a selection of short films curated by Visualizing Abolition Visiting Faculty Fellow Dr. Pooja Rangan.
Prisons deny and censor the access of those trapped inside them—to information, to intimacy, to community, to meaningful work, to nourishment of all kinds, and perhaps most cruelly, to care. This program assembles a series of films, including works by filmmakers incarcerated in California as well as others without that lived experience. Together, these works confront the debilitating impacts of these restrictions and reveal how the disabling logic of the prison is extended to other institutional spaces (the hospital, the university), turning access into a scarce commodity by enclosing what should be held in common. Questioning the carceral and state-sponsored productions of disability and accessibility, the short films together reveal the courage of people working despite limitations to produce collective access for one another, described simply and beautifully by disability justice activist Leah-Lakshmi Piepzna Samarasinha as “revolutionary love without charity.”
Thanh Tran
Dying in Prison, 2022
HD Video (color, sound), 3 minutes
Courtesy of the artist
Carolyn Lazard
Pre-Existing Condition, 2019
HD video (color, sound), 6 minutes
Courtesy of the artist and Trautwein Herleth3
Anthony Alejandrez
Another Rainy Day, 2023
Phone video (color, sound), 3 minutes
Courtesy of the artist
Jordan Lord
After…After… (Access), 2018
HD Video (color, sound), 16 minutes
Courtesy of the artist
Rahsaan “New York” Thomas
Friendly Signs, 2023
Video (color, sound) 21 minutes
Courtesy of Tommy Wickerd, Empowerment Ave & System Impact Media

Rules Are Not Neutral: Play As Sense-Making, Acts Of Resistance, And Imagining Otherwise
2026-07-09 12:00 - 17:00, 2026-07-16 12:00 - 17:00 | Eloise Pickard Smith Gallery, 11 Cowell Service Rd, Santa Cruz, CA, 95064
This exhibition brings together a range of analog games – including board, card, role-playing, and other participatory works – that engage social and political realities in different ways. The works span widely circulated commercial games to independently produced projects, one-of-a-kind artworks by artists, faculty, alumni, and students, and materials drawn from UC Santa Cruz Special Collections and Archives.
In part, the exhibition challenges the persistent assumption that games and play are detached from social and political life. On the contrary, game designers and artists across diverse perspectives and positions have long used play to engage questions of social systems, lived experience, and how power operates. This exhibition does not attempt to represent that full spectrum. Instead, it brings together a particular set of works that foreground how games can make systems visible, intervene in them, and imagine alternatives.
All games embody values, whether intentional or not.
– Mary Flanagan, game designer and scholar
Across all of these works, games are not only forms of entertainment, though they may be that as well. They are encountered in multiple ways: as objects, as systems, as artworks, and as experiences that unfold unpredictably through interaction. In each case, rules and constraints shape what participants can do. In these different forms, the works stage systems – such as housing and land ownership, capitalism, race and identity, civil rights and protest, fascism, and colonialism – in ways that are simplified and easy to see, opening space to recognize similar structures beyond the game. In this sense, the works suggest that rules are not neutral – they organize experience, distribute power, and produce meaning.
Games are the art of agency.
– C. Thi Nguyen, philosopher
The exhibition is intentionally dense. This abundance reflects the breadth of ways games operate across contexts, from activism and education to art and everyday life. While it celebrates creativity and difference, it also asks how these works engage critically with the structures that shape our lives.
Some works use rules to model systems, helping players understand how those systems operate. Others use play to rehearse action, asking players to practice navigating or challenging those systems. Still others turn toward speculation, inviting players to imagine alternative futures, worlds, and the systems that might shape them.
The imagination is an instrument of change.
– Ursula K. Le Guin, author
The focus on analog games reflects how they foreground materiality and shared physical presence. Played face-to-face, handled, read aloud, and experienced together, these works show how rules operate not in abstraction, but through lived, embodied experience.
Ultimately, the exhibition asks us to consider not only how games represent the world, but how they shape our engagement with it – and how through play, the social and political systems they model might be understood, challenged, and reimagined.
Games are not apolitical.
– Kishonna L. Gray, media scholar

Gallery Reception
May 15 from 1 to 4pm at the Eloise Pickard Smith Gallery

Art Friday
Hands-on art activities drawing from the current exhibition.
ALL ARE WELCOME regardless of skill level. Art supplies and free snacks are provided!

Carrión, H. (CSE) - Deep Learning Algorithms for Medical Image Representation Learning and Understanding
2026-07-09 13:30 - 15:30
AI-assisted clinical decisions in medicine, and particularly in dermatology, demand fine-grained understanding across diverse skin tones, body sites, and disease types, yet expert-annotated datasets are scarce, demographically imbalanced, and almost devoid of rare presentations. This dissertation develops four deep learning systems for this low-label, low-coverage regime. We introduce HealNet, which learns wound healing stages from longitudinal photographs without any human labels, reaching 90.6% downstream stage-classification accuracy on a small longitudinal cohort. The Fair, Efficient, and Diverse Diffusion (FEDD) model then leverages powerful diffusion-model embeddings to build a skin-tone-fair, data-efficient classifier for skin lesions, matching or exceeding state-of-the-art performance while using only 5-20% of available labels and contributing explicit skin-tone-stratified fairness evaluation of the work. Next, Controllable Generation of Diverse Dermatological Imagery (cgDDI) re-tasks this diffusion model to controllably synthesize skin-tone-balanced dermatological imagery, growing a small biopsy-confirmed dataset by over 400x and reaching state-of-the-art 90.9% accuracy and improved fairness in malignancy classification, with a +13.9% cross-dataset gain on the Fitzpatrick17k benchmark. Finally, we introduce D-Synth and DermDepth: a synthetic dermoscopic dataset with pixel-perfect 3D ground truth and a metric-scale foundation model that closes the loop into 3D dermatology, correcting metric scale error from over 16x to under 1.1x on real dermoscopic data and enabling single-photograph measurement of lesion reconstruction: size, area, and volume without specialized hardware. All data, code, and models are released openly to support reproducibility and ongoing fairness research.
Event Host: Héctor Carrión, Ph.D. Candidate, Computer Science & Engineering
Advisor: Narges Norouzi
Zoom: https://ucsc.zoom.us/j/96678782408?pwd=[REDACTED]
Passcode: [REDACTED]

Levine, R. (CSE) - Validating GPU Memory Consistency and Safety at Scale
2026-07-10 11:00 - 12:30 | Engineering 2, Engineering 2 1156 High Street, Santa Cruz, CA, 95064
Graphics Processing Units (GPUs) have become essential platforms for parallel computing, supporting applications far beyond graphics. Central to GPU programming models is its memory consistency specification (MCS), which defines the semantics of concurrent shared-memory operations and interacts with other language features to determine security guarantees such as memory safety. Understanding whether implementations conform to an MCS, and whether the MCS provides a sound abstraction of real hardware, is essential for reasoning about GPU programs and validating implementations.
This thesis develops techniques and large-scale studies for validating GPU memory consistency and memory safety. First, it introduces MC Mutants, a mutation testing methodology that systematically evaluates GPU MCS test environments. Applied to WebGPU, MC Mutants generates a suite of conformance tests and uncovers two implementation bugs. Next, it presents GPUHarbor, a browser- and Android-based framework for large-scale testing across commodity GPUs. GPUHarbor enables a study of 106 GPUs from seven vendors, reveals two previously unknown memory consistency bugs, and provides new insights into GPU behavior that inform subsequent architectural and security studies. Finally, this thesis presents SafeRace, a collection of security assessments and specification proposals for preserving WebGPU memory safety in the presence of data races. Evaluated across dozens of GPUs and 21 WebGPU compilation stacks, SafeRace identifies vulnerabilities in multiple GPU implementations, including one assigned a CVE, and proposes a validated path toward stronger memory safety guarantees in WebGPU.
Event Host: Reese Levine, Ph.D. Candidate, Computer Science & Engineering
Advisor: Tyler Sorensen
Zoom: https://ucsc.zoom.us/j/94641390195?pwd=[REDACTED]
Passcode: [REDACTED]

UCSC Farm U-Pick
2026-07-11 09:00 - 12:00 | UCSC Farm, 152 Farm Rd, Santa Cruz, CA, 95064
Come enjoy picking your own organic strawberries and/or flowers at the campus farm!
When: U-picks will take place on Saturdays from 9am to 12pm, July 11–August 22, or while supplies last. PLEASE NOTE that u-pick will not occur on Saturday, August 29.
Where: Free parking will be available in the Hay Barn lot or lot 115/116 during u-pick hours. Please do not park in the dirt lot at the farm’s back gate. Please walk to the check-in table near the strawberries/flowers at the farm to pre-pay and collect your u-pick container(s). We will have directional signage displayed. There is one ADA parking spot on the farm. The UCSC Farm has uneven, hilly terrain. If you require accommodations to fully participate, please email agroecology@ucsc.edu.
Cost: UCSC students with valid ID get 25% off produce.

Strawberry pints – $4 each
Strawberry flats (12 pints) – $44
Flowers, small bouquet – $5
Flowers, large bouquet – $15
Flower, bulk buckets – $65

Payment: Credit card payments only (you will need a smartphone to scan a QR code and enter your card info manually).
Dogs are not allowed on the UC Santa Cruz campus (service animals are OK).

Free Guided Tour of the UCSC Farm
2026-07-11 10:00 - 11:30 | UCSC Farm, 152 Farm Rd, Santa Cruz, CA, 95064
Take a free, guided tour of the 30-acre organic UCSC Farm. Visitors can enjoy touring the organically managed greenhouses, hand-worked garden beds, orchards, row crop fields, and children’s garden, while learning about the history of the site and the basic concepts of organic farming and gardening. Perched on a meadow near the campus entrance, the farm also offers spectacular views of the Monterey Bay. Heavy rain cancels.
Tours will take place from 10 a.m. to 11:30 a.m. on the following dates (please RSVP for the tour of your choice):

Saturday, July 11
Saturday, August 1
Saturday, September 12
Saturday, October 3

Scott, J. (CSE) - Mechanistic Specialization Does Not Guarantee Performance: Evidence from Dual AttentionTransformers
2026-07-13 10:00 - 12:00
Dual Attention Transformers (DATs) extend decoder-only Transformers with a dedicated relational-attention stream, making them a natural architecture for abstract identity rules such asABA and ABB. Surprisingly, we find that comparably sized GPT-2 models outperform DATs on these tasks. We investigate this gap with two complementary mechanistic analyses. First, causal mediation analysis shows that DATs exhibit stronger evidence of hypothesized symbolic mechanisms: symbol abstraction, symbol induction, and retrieval, than GPT-2. Second, a routing analysis shows why this specialization does not translate into better behavior: DATs make more wrong-copy errors, can attend to the correct source token while still predicting the wrong token, and show weak direct contribution from relational attention to the correct-versus-wrong outputmargin. Ablating positive-routing heads hurts performance, while amplifying those headsimproves DAT more than matched controls. These results show that explicit relational attentioncan shape internal organization without guaranteeing task success. For identity-rule tasks, performance depends not only on whether relational information is represented, but whether it is routed to the final output position in a form that affects the next-token prediction. Because pretrained DAT and GPT-2 models differ in training data, tokenizer, and other implementation details, these findings should be interpreted as evidence about the mechanisms used by existing models rather than as a definitive architectural comparison. Follow-up experiments will address these confounders through controlled training comparisons that match data, scale, and evaluation conditions across architectures.
Event Host: Jonathan Scott, Ph.D. Student, Computer Science & Engineering
Advisor: Leilani Gilpin
Zoom: https://ucsc.zoom.us/j/95404396322?pwd=[REDACTED]
Passcode: [REDACTED]

Kembay, A. (ECE) - Sparse and Continual Foundations for Adaptive General Intelligence
2026-07-13 16:00 - 17:00 | Engineering 2, Engineering 2 1156 High Street, Santa Cruz, CA, 95064
While the human brain learns continually, mastering new tasks without forgetting
the old and adapting to unfamiliar ones from context alone, modern neural networks
still lack both. To bridge the gap between biological adaptivity and modern AI, we
have established foundational work on sparsity as a computational principle at three
levels of neural computation, through salient feature masking that distills only the most
informative knowledge from a teacher, quantized spiking neural networks whose sparse
activations mitigate catastrophic forgetting by updating weights only when new learn-
ing requires it, and complex-pole value-path dynamics that give Transformer attention
a resonant, positionally selective memory. Addressing the remaining bottleneck, that
these sparse structures are fixed in advance rather than adapted to the task at hand,
we propose a research roadmap centered on in-context meta-learning with sparse atten-
tion priors, enabling models to ‘learn to be sparse’ by inferring task-relevant structure
from context alone, without any weight update. Taken together, this research seeks
to unify brain-inspired sparsity with continual and in-context learning as a foundation
for adaptive general intelligence.
Event Host: Assel Kembay, Ph.D. Student, Electrical & Computer Engineering
Advisor: Jason Eshraghian
Zoom: https://ucsc.zoom.us/j/92202931005?pwd=[REDACTED]
Passcode: [REDACTED]

July Slugs and Steins with Assistant Professor Aide Macias-Munoz
2026-07-13 18:30 - 20:00
Unlocking the blueprint for regeneration: Insights from Hydra
Regeneration, the ability to heal and regrow lost body parts, varies across species, tissues, and even cell types. To harness regenerative ability for medicine, we need to understand the genetic mechanisms that are similar across regenerating species. My lab uses Hydra, a small freshwater relative of jellyfish, to investigate how the genome controls this extraordinary process. Hydra possess remarkable regenerative abilities, including the capacity to regenerate head and foot when cut in half and to rebuild a complete animal from clusters of cells. By studying gene expression and gene regulation during regeneration, we aim to identify the genetic programs that drive this process. In this talk, I will discuss what Hydra can teach us about the evolution and genetic basis of regeneration.
Aide Macias-Muñoz is an Assistant Professor in the Department of Ecology and Evolutionary Biology at UC Santa Cruz. Her research seeks to understand how complex traits, including regeneration and eyes, have evolved across animals. She is particularly interested in deciphering whether similar or different genes are used to encode these traits in different species. She holds a B.A. in Integrative Biology with a minor in Chicana/o Studies from the University of California, Berkeley and a Ph.D. from the University of California, Irvine.
REGISTER

Volunteer at the UCSC Arboretum
2026-07-14 10:00 - 11:00 | Arboretum, 122 Arboretum Road, Santa Cruz, CA, 95064
Volunteer Information Sessions at the Arboretum
Do you love gardens and gardening? The UCSC Arboretum & Botanic Garden has a wonderful community of staff, students, and volunteers, ready to welcome you. Opportunities include staffing our gift shop & retail nursery and working to care for our gardens and greenhouses.
To learn more, join us at one of our monthly information sessions. They go for about 45 minutes and include an easy walk through the gardens.
To attend, please fill out our simple volunteer interest form at the bottom of our volunteer webpage found here: https://arboretum.ucsc.edu/get-involved/become-a-volunteer/
If you need a different day and/or have mobility issues please let us know in the “Notes” section of the Interest Form.
Thank You!

Note Taking and Reading Strategies
2026-07-14 13:00 - 13:45 | https://ucsc.zoom.us/j/7372922776?pwd=[REDACTED]
In this workshop, you will: Learn reading and note-taking methods and why they work to help you learn.
The Successful Slug Workshop series, hosted by Learning Support Services Peer Coaches, are open to all UCSC undergraduate students and focus on academic skills and tools to support your success as a student. At each workshop, you will be introduced to a topic, engage in active learning, be given resources to begin implementing the same day, and have an opportunity to learn more if you are interested.
You Belong Here: The programs and services described here are open to all, consistent with state and federal law, as well as the University of California’s nondiscrimination policies. Every initiative—whether a student service, faculty program, or community event—is designed to be accessible, inclusive, and respectful of all identities.
To learn more, please visit UC Nondiscrimination Statement or Nondiscrimination Policy for UC Publications.

Post Grad Job Search: Build a Standout Resume with AI
2026-07-14 13:00 - 14:00 | CA
Life After Graduation Series
Hosted by UC Davis and COOP Careers, open to recent alumni and rising seniors of all UC campuses.
Join the Cal Aggie Alumni Association for another session in the Life After Graduation Series, “Post-Grad Job Search: Build a Standout Resume with AI,” presented by COOP Careers, on Tuesday, July 14 at 1:00 p.m. (Pacific Time).
This hands-on session is designed specifically for recent graduates navigating the post-college job search.
Learn how to combine the efficiency of AI with the authenticity of your personal story to create a resume that feels both polished and personal. Whether you’re applying for your first full-time role or actively exploring early career opportunities, you’ll leave with practical tools you can use immediately.
In this session, you will learn how to:

Leverage AI tools strategically to generate, refine, and tailor resume content for entry-level roles
Translate academic and professional experiences into compelling, results-oriented resume bullet points
Apply best practices in resume formatting and storytelling to create a polished, industry-ready resume
Use AI to customize resumes for specific job descriptions
Bonus (if time permits): Use AI as a support tool for interview preparation, including generating practice questions and crafting strong responses

REGISTER HERE

Resume and Cover Letter Workshop
2026-07-14 16:30 - 18:00 | https://ucsc.zoom.us/j/9300281173?pwd=[REDACTED]
Having a fantastic resume and cover letter are the first steps towards securing a great job or internship. Join us for this informative workshop to learn current best practices for creating or updating your resume and cover letter.
Topics include:

Tailoring your resume to the job description
Formatting tips
Creating impactful bullet points
Writing a relevant and meaningful cover letter

RSVP on Handshake
YOU BELONG HERE
Programs and services are open to all, consistent with state and federal law, as well as the University of California’s nondiscrimination policies. Every initiative—whether a student service, faculty program, or community event—is designed to be accessible, inclusive, and respectful of all identities. To learn more, please visit UC Nondiscrimination Statement or Nondiscrimination Policy for UC Publications.

A New Graduate's Guide to Investing
2026-07-15 12:00 - 13:00 | CA
Life After Graduation Series
Hosted by UC Davis, open to recent alumni and rising seniors of all UC campuses.
Join the Cal Aggie Alumni Association for another session in the Life After Graduation Series, “A New Graduate’s Guide to Investing,” on Wednesday, July 15 at 12:00 p.m. (Pacific Time).
This practical workshop is designed to help new alumni understand how investing can support their short- and long-term financial goals. Participants will learn the fundamentals of investing—including risk, diversification, and how to get started—so they can build confidence and make informed decisions early in their post-graduation journey.
LEARN MORE & REGISTER

Beyond the Algorithm: How to Get Noticed When Everyone Is Using AI
2026-07-15 18:00 - 19:00 | CA
Beyond the Algorithm: How to Get Noticed When Everyone Is Using AI With Armine Kulikyan
Wednesday, Jul. 15 | 6 p.m. (PT)
Virtual via Zoom
Hosted by UCLA Alumni Association, open to all UC alumni
A career workshop teaching alumni how to use AI strategically to stand out, not blend in.
LEARN MORE & REGISTER

Santa Cruz Shakespeare Opening Night
2026-07-16 20:00 | The Audrey Stanley Grove in Delaveaga Park, 501 Upper Park Rd, Santa Cruz, 95065, United States
Tickets are now on sale for Santa Cruz Shakespeare’s 2026 Season, featuring Much Ado About Nothing and Macbeth. Co-sponsored by the Humanities Institute.
The 2026 season runs from July 16 – August 30.
Much Ado About Nothing is one of Shakespeare’s wittiest and most beloved comedies. Of all the couples in Shakespeare, perhaps none is more widely loved than Beatrice and Benedick. Their battle of wits, their antagonism turned to eroticism, their history. Before the play begins, they already seem to define each other. The audience, like the other characters in the play, wait with excitement as their wits clash, and eventually, as their love blossoms.

Macbeth by William Shakespeare’s is one of the greatest plays ever written. Its central couple, ironically, is one of Shakespeare’s happiest. At least at the beginning. Macbeth explores what we become when our second half is ripped away. A powerful unit, wildly in love with each other, the Macbeths follow the insinuations of the witches – the famous weird sisters – and commit murder in the name of their shared ambition: the throne of Scotland. But even with their goal achieved, Macbeth’s paranoia and guilt lead him further down the road of blood. The central unit tears apart under the shadow of its deeds. Who are these two without each other? Slowly and surely, the play shows us society’s ruin in the form of its leading pair.
Santa Cruz Shakespeare’s production of Macbeth stars Dan Donohue in the title role and Paige Lindsey White as Lady Macbeth.

Calicchio, A. (BMEB) - Comparison of long-read sequencing and analysis methods for transcriptome analysis
2026-07-17 11:30 - 13:30 | Biomedical Sciences Building, 575 McLaughlin Drive
Alternative splicing, the process generating different RNA isoforms from a single gene, is considered one of the main factors driving increased organism complexity in eukaryotes. Variations in isoform and gene expression produce the functional differences that give rise to different cell types and, in some cases, result in disease. Long-read RNA sequencing has transformed our ability to characterize isoforms, since single reads can span full-length transcripts, but limitations still prevent our identification of all the isoforms in the human transcriptome. Our research proposes to improve both the library preparation and computational analysis steps of the isoform identification process.
To do so, we are updating the isoform identification and quantification tool IG28 (previously called Mandalorion) so that it can analyse both bulk and single-cell long-read sequencing data and. By pairing our analysis with single-cell clustering in Seurat, we can generate transcriptomes for hundreds of thousands of single cells, for individual cell types, and for bulk datasets containing hundreds of millions of reads, providing a scalable approach to identify isoforms in the largest and most recent datasets.
Furthermore, since long reads can carry both the variants defining an allele of origin and the full isoform structure, we plan to extend IG28 to perform allele-specific transcript usage analysis. We plan to include accurate statistical tests in this module by using beta-binomial and Dirichlet-multinomial models that account for overdispersion, to provide a tested and integrated pipeline for isoform allelic assignment.
Finally, recognizing that isoform detection depends on the quality, length, and throughput of the input data, we are improving library preparation and benchmarking sequencing technologies. We are refining the R2C2 protocol coupled with size selection to overcome the current circularization limit for fragments beyond 6 kb, and we are generating matched datasets to compare R2C2 to the Kinnex library preparation method, and ONT against PacBio HiFi sequencing, to determine which approaches produce the most accurate and longest reads for isoform identification.
Together, these advances will provide a competitive pipeline, from cDNA preparation to isoform identification and annotation, enabling accurate isoform annotations that can lead to a deeper understanding of cell differentiation and disease etiology.
Event Host: Alessandro Calicchio, Ph.D. Student, Biomolecular Engineering & Bioinformatics
Advisor: Christopher Vollmers
Zoom: https://ucsc.zoom.us/j/92704819548?pwd=[REDACTED]
Passcode: [REDACTED]
