Applied Math Department

Presenter: Dr. Aw, Department of Genetics, University of Pennsylvania Description: Admixed groups consist of individuals descended from two or more historically separated ancestral populations, and they are underrepresented in biomedical studies. Admixed individuals are unique in that they carry mosaics of ancestral segments within their genome, so their genetic information is typically summarized as a […]

Presenter: Marcos Calegari Andrade, Assistant Professor, Chemistry and Biochemistry, UC Santa Cruz Description: In this talk, I will demonstrate how neural networks can represent the high-dimensional potential energy surfaces of many-body systems. By achieving the accuracy of first-principles quantum calculations at a fraction of the computational cost, these models enable atomistic simulations of condensed matter […]

Presenter: Dr. Pulkit Dubey, Postdoc, UC Santa Cruz Description: Neural climate emulators such as NeuralGCM and LUCIE offer efficient, differentiable alternatives to General Circulation Models (GCMs), producing climate predictions at a fraction of the cost. While work to date has focused largely on predictive accuracy, we leverage differentiability to study control of long-horizon climatological targets. […]

Presenter: Anil Damle, Associate Professor, Cornell University Description: The column subset selection problem is a classical topic in numerical linear algebra, with renewed interest driven by applications in computational quantum chemistry, integral equations, model reduction, and model compression in machine learning. This talk surveys recent advances that clarify how structural properties of a matrix influence […]

Presenter: Dr. David A. Knowles, New York Genome Center & Columbia University Description: Many human diseases have a substantial genetic component, which association studies are increasingly capable of characterizing, empowered by ever-growing sample sizes. These associations have the potential to elucidate complex disease biology and prioritize therapeutic interventions. However, it is challenging to determine the […]

Presenter: Denis Titov, Assistant Professor, University of California, Berkeley Description: Cells run thousands of chemical reactions simultaneously, and these reactions must be precisely controlled—like a thermostat that prevents overheating. When this control fails, diseases including diabetes, cardiovascular disease, and fatty liver disease result. One key control mechanism is allosteric regulation, where a small molecule binds […]