• Imlau Dagostini, J. (CSE) – Intent-Driven Orchestration for Scientific Computing

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA
    Hybrid Event

    The growing complexity of high-performance computing (HPC) systems poses a fundamental challenge for domain scientists, whose primary objective is to obtain scientifically valid results rather than to optimize resource utilization. Modern leadership-class facilities combine heterogeneous CPUs, GPUs, and specialized accelerators across systems that simultaneously support traditional scientific simulations and AI-driven workloads. This creates a vast, […]

  • Figuerres, S. (ECE) – Ion Transport Mechanisms for Bioelectronics

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Ion transfer as the movement of charged species across spaces and interfaces is the basis of signaling in nearly all biological systems. My research is grounded in the idea that precise control over ion transfer enables direct manipulation of biological function. Specifically, I focus on how ion transport can be engineered to regulate both collective […]

  • Statistics Seminar: From Random Walks to Planning-Ready World Models: A Normative Model of Place Cells

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Deqian Kong, PhD student, UCLA Description: How does the hippocampus turn experience into a cognitive map that is not just a passive record of space but a representation ready for planning? In this talk, I will present a normative model in which place cells emerge as a non-negative population embedding whose inner products approximate […]

  • AM Seminar: Using Math and Experiments to Study the Control of Cell Metabolism

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Denis Titov, Assistant Professor, University of California, Berkeley Description: Cells run thousands of chemical reactions simultaneously, and these reactions must be precisely controlled—like a thermostat that prevents overheating. When this control fails, diseases including diabetes, cardiovascular disease, and fatty liver disease result. One key control mechanism is allosteric regulation, where a small molecule binds […]

  • AM Seminar: Dissecting Complex Disease Mechanisms with Causal Inference and Deep Learning

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Dr. David A. Knowles, New York Genome Center & Columbia University Description: Many human diseases have a substantial genetic component, which association studies are increasingly capable of characterizing, empowered by ever-growing sample sizes. These associations have the potential to elucidate complex disease biology and prioritize therapeutic interventions. However, it is challenging to determine the […]

  • Statistics Seminar: Unifying Regression-Based and Design-Based Causal Inference in Time-Series Experiments and Crossover Experiments

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Peng Ding, Associate Professor, UC Berkeley Description: I will present some recent results on unifying regression-based and design-based causal inference in time-series experiments and crossover experiments. Part I: Time-series experiments, also called switchback experiments or N-of-1 trials, play increasingly important roles in modern applications in medical and industrial areas. Under the potential outcomes framework, […]

  • Statistics Seminar: Learning under Constraints and Extremes: Methods and Applications in Energy Systems

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Yu Zhang, Associate Professor, ECE Department of UC, Santa Cruz Description: Modern cyber-physical systems present statistical learning problems that deviate significantly from standard i.i.d. supervised settings. In particular, two challenges frequently arise: (i) learning under hard structural constraints, and (ii) learning under severe distributional imbalance and rare events. In this talk, I present two […]

  • AM Seminar: Column Subset Selection: Theory, Structure, and Algorithms

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Anil Damle, Associate Professor, Cornell University Description: The column subset selection problem is a classical topic in numerical linear algebra, with renewed interest driven by applications in computational quantum chemistry, integral equations, model reduction, and model compression in machine learning. This talk surveys recent advances that clarify how structural properties of a matrix influence […]

  • Wang, Q. (STAT) – Modern Statistical Methods for Modeling Spatial and Temporal Processes

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA
    Hybrid Event

    Modern scientific studies increasingly rely on complex datasets exhibiting spatial and temporal dependence, particularly in social, environmental, and climate applications. This dissertation develops statistical models and computational methods for analyzing such data, with an emphasis on capturing dependence structures, nonlinear dynamics, and uncertainty quantification. A spatial deep learning framework is developed to extend classical geostatistical […]

  • AM Seminar: Engineering the Earth’s Climate

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Dr. Pulkit Dubey, Postdoc, UC Santa Cruz Description: Neural climate emulators such as NeuralGCM and LUCIE offer efficient, differentiable alternatives to General Circulation Models (GCMs), producing climate predictions at a fraction of the cost. While work to date has focused largely on predictive accuracy, we leverage differentiability to study control of long-horizon climatological targets. […]

  • Statistics Seminar: Advancing Statistical Rigor in Single-Cell and Spatial Omics Using In Silico Control Data

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Guan’ao Yan, Assistant Professor, Michigan State University Description: Single-cell and spatial transcriptomics technologies now let us map cellular diversity and tissue organization at high resolution, but the computational methods built to analyze these data are difficult to evaluate in a rigorous, reproducible way. Two key barriers are the lack of realistic synthetic data with […]

  • AM Seminar: Machine Learning in Molecular Simulations: From Free Energy to Vibrational Spectroscopy

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Marcos Calegari Andrade, Assistant Professor, Chemistry and Biochemistry, UC Santa Cruz Description: In this talk, I will demonstrate how neural networks can represent the high-dimensional potential energy surfaces of many-body systems. By achieving the accuracy of first-principles quantum calculations at a fraction of the computational cost, these models enable atomistic simulations of condensed matter […]

  • Statistics Seminar: Active Learning for Fair and Stable Allocations

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Presenter: Riddhiman Bhattacharya, Postdoc, UCSC Description: We propose an active learning approach for dynamic fair resource allocation problems. In contrast to prior work that assumes full feedback from all agents on their allocations, we focus on scenarios where feedback is available only from a carefully select subset of agents at each epoch of the online […]

  • DNA Day

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    Join the UCSC Genomics Institute in our annual celebration of DNA!