• BME 280B Seminar: The evolution of structural variation across vertebrate genomes

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Peter Sudmant, Assistant Professor of Integrative Biology, University of California, Berkeley Description: Structural variants (SVs) contribute substantially to genetic variation and play vital roles in adaptation and disease. However, SVs are poorly captured by short read sequencing and thus are understudied, particularly in non-model organisms. Here, taking advantage of recently generated haplotype-resolved genome assemblies […]

  • BME Seminar: Population Genetics in an Era of Genomic Health

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Dr. Eimear Kenny, Founding Director of the Institute for Genomic Health and a Endowed Chair and Professor for Genomic Health at the Icahn School of Medicine at Mount Sinai Description: The overarching goal of my work is to advance genomics in medicine and research through diversity and innovation. The work of my group seeks […]

  • BME 280B Seminar: Satellite repeats encode megabase-scale transcription factor hubs

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Matt Franklin, Postdoctoral Researcher, Stanford University Description: Eukaryotic genomes contain large stretches of repetitive DNA called satellite DNA, often found near centromeres and ribosomal DNA regions. In humans, alpha satellite has well-established roles in centromere biology, however the functions of other human satellite DNAs remain largely unexplored. We recently identified the Hippo pathway effector […]

  • BME Seminar: Rotation Talks

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Grad Students Description: Rotation Talks Bio: N/A Hosted by: Professor Rebecca DuBois, BME Department

  • BME 280B Seminar: Nature’s Miniature Masterpieces – Nanobodies as Small but Mighty Antibodies for the next Pandemic

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Katja Hanack, Founder and CEO, New/Era/Mabs Description: Nanobodies combine remarkable simplicity with surprising power. Their small size allows them to reach targets that remain inaccessible to conventional antibodies, while maintaining high specificity and stability. Their compact architecture allows them to access targets that conventional antibodies cannot reach, yet they preserve the specificity and power […]

  • BME 280B Seminar: Gali Bai & David Haussler

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter 1: Gali Bai, BME/PBSE Doctoral Candidate, Brooks Lab, UC Santa Cruz Title 1: Dissecting the contribution of chromatin accessibility to RNA transcription and processing with long-read sequencing Description: Although all cells in an organism share the same genomic sequence, transcriptional programs vary dramatically across cell types. This diversity is governed by epigenetic regulation involving […]

  • BME 280B Seminar: Anne Nakamoto, Alan Zhang, Shelbi Russell

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter 1: Anne Nakamoto, BME PhD Candidate, Corbett-Detig Lab, UC Santa Cruz Talk: Investigating deleterious mutation burden across populations and landscapes in the California Conservation Genomics Project Description: Biodiversity is being lost at an accelerated rate due in part to anthropogenic forces, posing a threat to the sustainability of Earth’s ecosystems as well as to human […]

  • BME 280B Seminar: Preconfigured neuronal firing sequences in human brain organoids

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Tjitse (TJ) van der Molen, Ph.D. (Postdoc, Sharf Lab, UC Santa Cruz and PhD Kosik Lab, UC Santa Barbara) Description: Neuronal firing sequences are thought to be the building blocks of information and broadcasting within the brain. Yet, it remains unclear when these sequences emerge during neurodevelopment. Here we demonstrate that structured firing sequences […]

  • BME 280B Seminar: Computational Models of Biological Systems

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Chen-Hsiang Yeang, Associate Research Fellow, Institute of Statistical Science of Academia Sinica Description: Computational models are roughly categorized into two types: describing the patterns of the phenomenon or data (description-driven models) and explaining the phenomenon or data with simpler, comprehensible rules (explanation-driven models). When building a model, the choice of the mixture ingredients of […]

  • BME 280B Seminar: Computational Precision Health & Genomic Diversity

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Dr. Alex Ioannidis, BME Assistant Professor, UCSC Description: N/A Bio: Alex Ioannidis graduated summa cum laude in Chemistry and Physics from Harvard and completed an M.Phil in Computational Biology in the Dept. of Applied Math & Theoretical Physics at Cambridge. He earned his Ph.D. in Computational & Mathematical Engineering at Stanford and M.S. in […]

  • BME 280B Seminar: Applying a translational research framework to understand PFAS exposures and health risks

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA

    Presenter: Dr. Max Aung, Assistant Professor of Environmental Health, USC Keck School of Medicine Description: Per and poly-fluoroalkyl substances (PFAS) are a group of industrial chemicals that are ubiquitous in the environment and in humans. The National Academies of Science, Engineering, and Medicine, have identified PFAS as an important environmental risk factor for various chronic […]