Calicchio, A. (BMEB) – Comparison of long-read sequencing and analysis methods for transcriptome analysis
Alternative splicing, the process generating different RNA isoforms from a single gene, is considered one of the main factors driving increased organism complexity in eukaryotes. Variations in isoform and gene expression produce the functional differences that give rise to different cell types and, in some cases, result in disease. Long-read RNA sequencing has transformed our […]