Translation is a central and highly regulated step of gene expression, yet there are few quantitative, high-throughput tools to study translation. Existing methods such as sucrose gradients provide only bulk […]
Transcriptomic profiling has been transformative in pediatric oncology. Pediatric cancers arise from disrupted developmental programs. Their impaired transcriptional states reflect cell lineage infidelity, aberrant differentiation, and immune-microenvironment interactions distinct from those of adult tumors(Gröbner et al., 2018; X. Ma et al., 2018). Within the osteosarcoma (OS) landscape, despite being the most common bone tumor of […]
Today, both individual and collective memories are increasingly mediated by digital platforms. Both are fundamentally enmeshed in platform ecosystems that orient around commercial imperatives very much at odds with community cohesion. The digital archive where our mediated memories are stored does not merely store information but actively inscribes it, often privileging narratives aligned with commercial […]