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  • Close-up abstract image of a circuit board with glowing lines and interconnected pathways.

    Abdulaziz, A. (ECE) – Learning-Based Channel Estimation for Next-Generation Wireless Communications

    Engineering 2 Engineering 2 1156 High Street, Santa Cruz, CA
    Hybrid Event

    Coherent wireless reception depends on accurate channel state information (CSI), yet acquiring CSI through pilot transmission consumes time–frequency resources that could otherwise carry data. This tradeoff becomes more pronounced in time-varying and frequency-selective channels and in short-packet communications, where accurate channel estimation is challenging and pilot overhead can be significant. This dissertation investigates how CSI […]

  • Close-up abstract image of a circuit board with glowing lines and interconnected pathways.

    Mirzanezhad, H. (EE) – Van der Waals materials-based memory devices for neuromorphic computing

    Jack Baskin Engineering Baskin Engineering 1156 High Street, Santa Cruz, CA

    The separation of memory and processing in conventional computer architectures leads to significant energy consumption associated with data transfer, known as the von Neumann bottleneck. Two-dimensional (2D) materials provide a promising platform for developing nanoscale memory devices for in-memory and neuromorphic computing because of their atomic-scale thickness, lack of dangling bonds, and ability to form […]

  • Three silhouetted figures talking, overlaid with graphics of digital data, charts, and technology interfaces.

    Tornoe, S. (ECE) – Improving the UV optical response and suppressing surface plasmon resonance in aluminum and silver base telescope mirrors

    2300 Delaware Avenue 2300 Delaware Ave, Santa Cruz, CA
    Hybrid Event

    Aluminum and silver are excellent metal-bases for astronomical telescopes designed for broadband spectral measurements. In particular silver excels in the violet to infrared spectral range range with over 95% reflectance. In turn aluminum excels deep ultra-violet to infrared with over 90% reflectance across the bulk of its spectral range. In astronomical telescope optics, each percent […]

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    Mastoras, M. (BMEB) – Polishing genome assemblies and leveraging their improved quality to study centromere variation

    Physical Sciences Building Physical Sciences Building, Santa Cruz, CA
    Hybrid Event

    A complete and accurate genome reconstruction serves as the foundation for studying an organism’s biology and the mechanisms underlying disease. It is particularly critical for reference genomes, which provide a universal coordinate system for downstream genomic analysis. Errors or missing sequences in a reference genome create bias in all of the studies built on top […]

  • Three silhouetted figures talking, overlaid with graphics of digital data, charts, and technology interfaces.

    Malekos, E. (BMEB) – CRISPR screens of noncanonical ORFs uncover retroviral-derived immune regulators

    Biomedical Sciences Biomedical Sciences Building Red Hill Road, Santa Cruz, CA

    Ribosome profiling has revealed thousands of noncanonical translation events across mammalian genomes, yet functional characterization has overwhelmingly focused on proliferative fitness in cancer cell lines. Here, we present a comprehensive survey of noncanonical translation in the mouse immune system and its functional consequences in macrophages. By performing a unified Ribo-seq meta-analysis across 20 public mouse […]

  • Abstract digital illustration featuring gears and interconnected technology elements.

    Heath, H. (BMEB) – Linking Altered mRNA Processing to Translational Regulation in Lung Cancer

    Biomedical Sciences Biomedical Sciences Building Red Hill Road, Santa Cruz, CA
    Hybrid Event

    In lung cancer, recurrent alterations in RNA processing regulators reshape both the proteins genes encode and the sequences that regulate their production. Understanding how mRNA processing influences protein production requires resolving the coding and regulatory sequences present in individual mRNA isoforms. Transcription start site (TSS) choice, alternative splicing (AS) , and polyadenylation site (PAS) choice […]