7 events found.
Mastoras, M. (BMEB) – Polishing genome assemblies and leveraging their improved quality to study centromere variation
Physical Sciences Building Physical Sciences Building, Santa Cruz
Hybrid Event
Malekos, E. (BMEB) – CRISPR screens of noncanonical ORFs uncover retroviral-derived immune regulators
Biomedical Sciences Biomedical Sciences Building Red Hill Road, Santa CruzWeek of Events
Monday, September 21, 2026
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September 21, 2026Headrick, C. (BMEB) – The Regulation of mRNA Cleavage in Nonsense-mediated mRNA Decay: From Inside (intra-pathway determinants) Out (extra-pathway regulation)
Headrick, C. (BMEB) – The Regulation of mRNA Cleavage in Nonsense-mediated mRNA Decay: From Inside (intra-pathway determinants) Out (extra-pathway regulation)
Nonsense-mediated mRNA decay (NMD) is a translation-coupled quality control pathway that degrades mRNAs that harbor a premature termination codon (PTC) and 5-30% of normal cellular mRNAs. The NMD field sits at a pivotal moment with recent developments that endonucleolytic cleavage is the primary mechanism of mRNA decay conserved across metazoans. Discovery of a conserved NMD […]
Tuesday, September 22, 2026
No events on this day.
Wednesday, September 23, 2026
No events on this day.
Thursday, September 24, 2026
No events on this day.
Friday, September 25, 2026
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Hybrid EventSeptember 25, 2026Mastoras, M. (BMEB) – Polishing genome assemblies and leveraging their improved quality to study centromere variation
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September 25, 2026Malekos, E. (BMEB) – CRISPR screens of noncanonical ORFs uncover retroviral-derived immune regulators
Hybrid Event
Mastoras, M. (BMEB) – Polishing genome assemblies and leveraging their improved quality to study centromere variation
A complete and accurate genome reconstruction serves as the foundation for studying an organism’s biology and the mechanisms underlying disease. It is particularly critical for reference genomes, which provide a universal coordinate system for downstream genomic analysis. Errors or missing sequences in a reference genome create bias in all of the studies built on top […]
Malekos, E. (BMEB) – CRISPR screens of noncanonical ORFs uncover retroviral-derived immune regulators
Ribosome profiling has revealed thousands of noncanonical translation events across mammalian genomes, yet functional characterization has overwhelmingly focused on proliferative fitness in cancer cell lines. Here, we present a comprehensive survey of noncanonical translation in the mouse immune system and its functional consequences in macrophages. By performing a unified Ribo-seq meta-analysis across 20 public mouse […]
Saturday, September 26, 2026
No events on this day.
Sunday, September 27, 2026
No events on this day.