Torres, S. (ECE) – An Integrated Platform for Real-time Monitoring and Support of 3D Tissue Growth
Organoids are three-dimensional tissue cultures that model real organs and serve as valuable tools for studying development, disease, and treatment response. Traditional methods, which rely on manual handling and incubators, limit consistency and real-time monitoring. To address these issues, we developed a modular microfluidic platform that integrates automated feeding, live fluorescence imaging, and environmental control without the need for a standard incubator. The core of the system is a vertically oriented PDMS-glass chip that enables precise media delivery and continuous imaging of small 3D structures such as organoids. Using fluorescent dyes to mimic molecules, such as nutrients or drugs, we tracked their movement through tissue in real time without invasive sensors. This setup maintains metabolic stability and provides detailed insight into molecular transport, which improves applications in disease modeling, drug testing, and personalized medicine.
Event Host- Sebastián Torres, Ph.D. Candidate, Electrical & Computer Engineering
Advisor: Mircea Teodorescu
Zoom- https://ucsc.zoom.us/j/
Passcode- 579836
